It is of great significance to study hydrochemical characteristics and origin of groundwater in Rizhao section in Jiaonan uplift for the development and protection of groundwater resources. Based on comprehensive analysis of hydrogeological conditions in Rizhao section in Jiaonan uplift area, 71 groups of groundwater samples from the research area have been collected systematically. By using descriptive statistics, Piper plots, Gibbs plots, correlation analysis and ion ratio method, spatial distribution, hydrochemical characteristics and origin of groundwater chemistry have been analyzed. It is showed that groundwater in Rizhao section in Jiaonan uplift area is generally weak alkaline, with HCO3 as main anion, and Ca2+and Na+as main cations. The ion content in loose rock pore water is relatively stable, while Ca2+and HCO3 content in bedrock fissure water are relatively stable. The content of other anions and cations in groundwater varies greatly. The groundwater chemical types are complex and diverse, including HCO3, HCO3·SO4, and HCO3·Cl type water. Their distribution shows a distinct zonation from the recharge area to the discharge area. The pore water and bedrock fissure water within the area are mainly controlled by water rock interactions, and the ion source is mainly the dissolution of silicate rocks.